Holiday Inn St. Louis Southwest Route 66

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About

Get Your Kicks on Route 66! With a convenient location along Historic Route 66 in Sunset Hills, the Holiday Inn St. Louis SW – Route 66 offers the best accommodations in town. At the junction of I-44 and I-270, the hotel is located less than two miles from Historic Kirkwood, and just 14 miles from the Gateway Arch and all the exciting attractions downtown St. Louis has to offer. Stay and play in St. Louis and experience a Cardinals game at Busch Stadium, a Blues game at Enterprise Arena, or come show your support for one of your most favorite traveling teams at the World Wide Technology Soccer Park. A visit to St. Louis wouldn’t be complete without a stop by the ever-so-popular St. Louis Science Center, St. Louis Aquarium, Missouri Botanical Gardens, Magic House, Six Flags, or the nationally accredited St. Louis Zoo. The hotel is also just a short drive to Webster University, Harris-Stowe State University, St. Louis University, Barnes Jewish Hospital, St. Louis Children’s Hospital, Mercy Hospitals, SSM, and Washington University’s top medical centers. Corporate and leisure travelers will be impressed with our newly renovated 213-room hotel and 15,500 square feet of flexible meeting space. Sunset Event Space, operated by Twisted Catering, will be the place to host meetings, weddings, and special events for years to come. Guests can also enjoy “Wakey Wakey a Breakfast Place” for a fresh start to the day, and lunch or dinner at the Award-Winning Twisted Tree Steakhouse adjacent to the hotel.

10709 Watson Rd.
St. Louis, MO 63127

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TripAdvisor Rating:

375 Reviews | Write a Review
Kim at the front desk rocks
Reviewed By Rachel C October 2024

I cannot say high enough praise for my experience here! I was helped at the front desk by Kim on October 29th and she went above and beyond to accommodate my needs. She was exceptionally helpful...

Full Review
Amazing Stay – Perfect for Families and Relaxation!
Reviewed By Kathleen K October 2024

We recently stayed at this hotel and were blown away by the remodel—everything feels fresh and modern! The heated pool was a big hit with our kids, and it was such a relaxing space for the whole...

Full Review
Hotel
Reviewed By Alex N October 2024

This hotel is one of the best places to stay around compared to the other hotels in the area the recent remodel was done very well I recommend the lounge being open on the Sundays but I understand...

Full Review
Handicap AccessiblePet FriendlySouth/SouthwestSouthwest

TripAdvisor Rating:

375 Reviews | Write a Review
Kim at the front desk rocks
Reviewed By Rachel C October 2024

I cannot say high enough praise for my experience here! I was helped at the front desk by Kim on October 29th and she went above and beyond to accommodate my needs. She was exceptionally helpful...

Full Review
Amazing Stay – Perfect for Families and Relaxation!
Reviewed By Kathleen K October 2024

We recently stayed at this hotel and were blown away by the remodel—everything feels fresh and modern! The heated pool was a big hit with our kids, and it was such a relaxing space for the whole...

Full Review
Hotel
Reviewed By Alex N October 2024

This hotel is one of the best places to stay around compared to the other hotels in the area the recent remodel was done very well I recommend the lounge being open on the Sundays but I understand...

Full Review